E34.8

Applicable To

• Pineal gland dysfunction

• Progeria

Approximate Synonyms

• Cyst of pineal gland

• Hutchinson-gilford syndrome

• Pineal cyst

• Progeria syndrome

Clinical Information

• A disease that produces rapid aging, beginning in childhood

• A very rare genetic disorder caused by mutations in the lmna gene. It is characterized by premature aging. Signs and symptoms include failure to thrive, limited growth, alopecia, wrinkled skin, small face, development of atherosclerosis, and heart disease. There is no cure for this condition. Individuals do not usually survive beyond their early twenties. Death usually occurs as a result of complications from atherosclerosis.

• An abnormal congenital condition, associated with defects in the lamin type a gene, which is characterized by premature aging in children, where all the changes of cell senescence occur. It is manifested by premature greying; hair loss; hearing loss deafness); cataracts cataract); arthritis; osteoporosis; diabetes mellitus; atrophy of subcutaneous fat; skeletal hypoplasia; elevated urinary hyaluronic acid; and accelerated atherosclerosis. Many affected individuals develop malignant tumors, especially sarcoma.

Details

• E34.8 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.

• The 2023 edition of ICD-10-CM E34.8 became effective on October 1, 2022.

• This is the American ICD-10-CM version of E34.8 – other international versions of ICD-10 E34.8 may differ.