A chronic granulomatous inflammation involving the deep dermis and the subcutaneous tissues. It is caused by fungi and actinomycetes.
A chronic progressive subcutaneous infection caused by species of fungi eumycetoma), or actinomycetes actinomycetoma). It is characterized by tumefaction, abscesses, and tumor-like granules representing microcolonies of pathogens, such as madurella fungi and bacteria actinomycetes, with different grain colors.