B00.4

Applicable To

• Herpesviral meningoencephalitis

• Simian B disease

Approximate Synonyms

• Encephalitis due to human herpes simplex virus

• Herpes simplex encephalitis

• Herpes simplex meningoencephalitis

• Herpetic meningoencephalitis

Clinical Information

• A serious viral disorder characterized by infection of the brain by herpes simplex virus type 1 or 2. Herpes simplex virus type 1 affects adults, whereas herpes simplex virus type 2 affects newborns. Signs and symptoms include fever, headaches, vomiting, seizures and psychiatric manifestations.

• An acute or rarely chronic) inflammatory process of the brain caused by simplexvirus infections which may be fatal. The majority of infections are caused by human herpesvirus 1 herpesvirus 1, human) and less often by human herpesvirus 2 herpesvirus 2, human). Clinical manifestations include fever; headache; seizures; hallucinations; behavioral alterations; aphasia; hemiparesis; and coma. Pathologically, the condition is marked by a hemorrhagic necrosis involving the medial and inferior temporal lobe and orbital regions of the frontal lobe. from Adams et al., Principles of Neurology, 6th ed, pp751-4)

Details

• B00.4 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.

• The 2023 edition of ICD-10-CM B00.4 became effective on October 1, 2022.

• This is the American ICD-10-CM version of B00.4 – other international versions of ICD-10 B00.4 may differ.