C81.0

Clinical Information

• A monoclonal b-cell neoplasm characterized by a nodular, or a nodular and diffuse, polymorphous proliferation of scattered large neoplastic cells known as popcorn or l&h cells; the l&h cells are cd15 negative, and rarely positive for cd30 antigen. Patients are predominantly male, frequently in the 30-50 year age group. Most patients present with limited stage disease localized peripheral lymphadenopathy, stage i or ii); the prognosis of patients with stage i and stage ii disease is very good. Advanced stages have an unfavorable prognosis.

• A rare type of hodgkin lymphoma, which is a cancer of the immune system. It is marked by the presence of a type of cell called a popcorn cell, which is different from the typical reed-sternberg cell found in classical hodgkin lymphoma. This type of hodgkin lymphoma may change into diffuse large b-cell lymphoma.

• A subtype of classical hodgkin lymphoma. Most patients present with peripheral lymphadenopathy and limited stage disease stage i or ii). The survival and progression free survival are slightly better than in other subtypes of classical hodgkin lymphoma. who, 2001)

Details

• C81.0 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.

• The 2023 edition of ICD-10-CM C81.0 became effective on October 1, 2022.

• This is the American ICD-10-CM version of C81.0 – other international versions of ICD-10 C81.0 may differ.