C91.3

Clinical Information

• A chronic leukemia characterized by a large number of circulating prolymphocytes. It can arise spontaneously or as a consequence of transformation of chronic lymphocytic leukemia.

• A malignant b-cell lymphoproliferative process affecting the blood, bone marrow, and spleen. The b-prolymphocytes are medium-sized, round lymphoid cells with prominent nucleoli. The b-prolymphocytes must exceed 55% of lymphoid cells in the blood. Cases of transformed chronic lymphocytic leukemia cll) and cll with increased prolymphocytes are excluded. The prognosis is poor. who, 2001)

• A mature b- or t- cell leukemia with progressive clinical course. It is characterized by the presence of medium-sized lymphocytes with visible nucleoli prolymphocytes) in the peripheral blood, bone marrow, and spleen.

• A neoplasm of prolymphocytes affecting the blood, bone marrow, and spleen. It is characterized by prolymphocytes exceeding 55% of the lymphoid cells in the blood and profound splenomegaly.

• A type of chronic lymphocytic leukemia cll) in which too many immature white blood cells prolymphocytes) are found in the blood and bone marrow. Pll usually progresses more rapidly than classic cll.

• Pll. A type of chronic lymphocyctic leukemia cll), in which too many immature white blood cells prolymphocytes) are found in the blood and bone marrow. Pll usually progresses more rapidly than classic cll.

Details

• C91.3 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.

• The 2023 edition of ICD-10-CM C91.3 became effective on October 1, 2022.

• This is the American ICD-10-CM version of C91.3 – other international versions of ICD-10 C91.3 may differ.