C92.0

Acute myeloblastic leukemia

A clonal expansion of myeloid blasts in the bone marrow, blood or other tissues. The classification of acute myeloid leukemias amls) encompasses four major categories: 1) aml with recurrent genetic abnormalities 2) aml with multilineage dysplasia 3) therapy-related aml 4) aml not otherwise categorized. The required bone marrow or peripheral blood blast percentage for the diagnosis of aml has been recently reduced from 30% french-american-british [fab] classification) to 20% who classification). who, 2001)

A quickly progressing disease in which too many immature blood-forming cells are found in the blood and bone marrow.

Acute leukemia arising from myeloid tissue in which the granular, polymorphonuclear leukocytes and their precursors predominate.

An acute myeloid leukemia aml) characterized by blasts with evidence of maturation to more mature neutrophils. Patients often present with anemia, neutropenia, and thrombocytopenia. Aml with the t 8;21) is usually aml with maturation. This type of aml frequently responds to aggressive therapy. who, 2001)

An acute myeloid leukemia aml) characterized by blasts without evidence of maturation to more mature neutrophils. The patients present with anemia, neutropenia, and thrombocytopenia. This type of aml usually follows an aggressive clinical course. who, 2001)

An acute myeloid leukemia aml) in which the blasts do not show evidence of myeloid differentiation by morphology and conventional cytochemistry. The myeloid origin of the blasts is demonstrated by immunohistochemistry and/or electron microscopic studies. The patients present with anemia, neutropenia, and thrombocytopenia. The prognosis is usually poor. who, 2001)

An aggressive fast-growing) disease in which too many myeloblasts immature white blood cells that are not lymphoblasts) are found in the bone marrow and blood.

Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce neutrophils; basophils; eosinophils; and monocytes.

Leukemia commonly occurring after alkylating agent treatment; manifestations include pancytopenia, megaloblastic bone marrow, and nucleated red cells in peripheral marrow; patients usually have chromosomal abnormalities in marrow cells.

leukemia is cancer of the white blood cells. White blood cells help your body fight infection. Your blood cells form in your bone marrow. In leukemia, however, the bone marrow produces abnormal white blood cells. These cells crowd out the healthy blood cells, making it hard for blood to do its work. In acute myeloid leukemia aml), there are too many of a specific type of white blood cell called a myeloblast.aml is the most common type of acute leukemia in adults. This type of cancer usually gets worse quickly if it is not treated. Possible risk factors include smoking, previous chemotherapy treatment, and exposure to radiation. Symptoms of aml include:

Refractory anemia with excess blasts in transformation raeb-t) is characterised by dysplastic features of the myeloid and usually erythroid progenitor cells in the bone marrow and an increased number of myeloblasts in the peripheral blood. The peripheral blood blast count ranges from 20% to 30%. Raeb-t used to be a subcategory of myelodysplastic syndromes in the past. Recently, the term has been eliminated from the who based classification of myelodysplastic syndromes. The reason is that the percentage of peripheral blood blasts required for the diagnosis of acute myeloid leukemia has been reduced to 20%. The elimination of the raeb-t term by the who experts has created confusion and ongoing arguments. Currently, according to who classification, the vast majority of raeb-t cases are best classified as acute leukemias acute leukemias with multilineage dysplasia following myelodysplastic syndrome). A minority of cases are part of raeb-2.

This term refers to acute myeloid leukemias that do not fulfill the criteria for inclusion in the group of acute myeloid leukemias which have recurrent genetic abnormalities or myelodysplastic changes, or are therapy-related. It includes entities classified according to the french-american-british classification scheme.

C92.0 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.

This is the American ICD-10-CM version of C92.0 – other international versions of ICD-10 C92.0 may differ.