D46.C

Applicable To

• Myelodysplastic syndrome with 5q deletion

• 5q minus syndrome NOS

Approximate Synonyms

• Myelodysplastic syndrome with 5q deletion

• Myelodysplastic syndrome with isolated del 5q)

Clinical Information

• A myelodysplastic syndrome characterized by a deletion between bands q31 and 33 on chromosome 5. The number of blasts in the bone marrow and blood is <5%. The bone marrow is usually hypercellular or normocellular with increased number of often hypolobated megakaryocytes. The peripheral blood shows macrocytic anemia. This syndrome occurs predominantly but not exclusively in middle age to older women. The prognosis is good and transformation to acute leukemia is rare. who, 2001)

• A rare disorder caused by loss of part of the long arm q arm) of human chromosome 5. This syndrome affects myeloid bone marrow) cells, causing treatment-resistant anemia, and myelodysplastic syndromes that may lead to acute myelogenous leukemia.

Details

• D46.C is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.

• Short description: Myelodysplastic syndrome w isolated del(5q) chromsoml abnlt

• The 2023 edition of ICD-10-CM D46.C became effective on October 1, 2022.

• This is the American ICD-10-CM version of D46.C – other international versions of ICD-10 D46.C may differ.