D47.1

Applicable To

• Chronic neutrophilic leukemia

• Myeloproliferative disease, unspecified

Approximate Synonyms

• Chronic myeloproliferative disorder clinical)

• Myeloproliferative disorder, chronic

Clinical Information

• A clonal hematopoietic stem cell disorder, characterized by proliferation in the bone marrow of one or more of the myeloid i.e., granulocytic, erythroid, megakaryocytic, and mast cell) lineages. It is primarily a neoplasm of adults. who 2008)

• A disease in which too many neutrophils a type of white blood cell) are found in the blood. The extra neutrophils may cause the spleen and liver to become enlarged. Chronic neutrophilic leukemia may stay the same for many years or it may progress quickly to acute leukemia.

• A group of slow growing blood cancers, including chronic myelogenous leukemia, in which large numbers of abnormal red blood cells, white blood cells, or platelets grow and spread in the bone marrow and the peripheral blood.

• A rare chronic myeloproliferative neoplasm characterised by neutrophilic leukocytosis. There is no detectable philadelphia chromosome or bcr/abl fusion gene.

• A rare myeloproliferative disorder that is characterized by a sustained, mature neutrophilic leukocytosis. No monocytosis, eosinophilia, or basophilia is present, nor is there a philadelphia chromosome or bcr-abl fusion gene genes, abl).

• Abnormal proliferation of hemopoietically active tissue or of tissue which has embryonic hemopoietic potential.

• Chronic myeloproliferative disorders cmpds) are clonal hematopoietic stem cell disorders, characterized by proliferation in the bone marrow of one or more of the myeloid i.e., granulocytic, erythroid, and megakaryocytic) lineages. The proliferation is associated with relatively normal, effective maturation, resulting in increased numbers of granulocytes, red blood cells, and/or platelets in the peripheral blood. Cmpds are primarily diseases of adults.

• Conditions which cause proliferation of hemopoietically active tissue or of tissue which has embryonic hemopoietic potential. They all involve dysregulation of multipotent myeloid progenitor cells, most often caused by a mutation in the jak2 protein tyrosine kinase.

Details

• D47.1 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.

• The 2023 edition of ICD-10-CM D47.1 became effective on October 1, 2022.

• This is the American ICD-10-CM version of D47.1 – other international versions of ICD-10 D47.1 may differ.