D81.810

Clinical Information

• A genetic disorder caused by mutations in the btd gene. It is characterized by reduced or absent activity of the enzyme biotinidase which is responsible for the recycling of the vitamin biotin. Signs and symptoms appear in childhood and include seizures, hypotonia and developmental delays. If left untreated, it leads to vision and hearing loss, infections, alopecia and ataxia.

• The late onset form of multiple carboxylase deficiency deficiency of the activities of biotin-dependent enzymes propionyl-coa carboxylase, methylcrotonyl-coa carboxylase, and pyruvate carboxylase) due to a defect or deficiency in biotinidase which is essential for recycling biotin.

Details

• D81.810 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.

• The 2023 edition of ICD-10-CM D81.810 became effective on October 1, 2022.

• This is the American ICD-10-CM version of D81.810 – other international versions of ICD-10 D81.810 may differ.