E16.9

Applicable To

• Islet-cell hyperplasia NOS

• Pancreatic endocrine cell hyperplasia NOS

Approximate Synonyms

• Disorder of pancreatic internal secretion

• Islet cell hyperplasia

• Pancreatic secretion disorder

Clinical Information

• A sporadic or inherited disorder characterized by the focal or diffuse proliferation of the cells of the islets of langerhans in the pancreas. It results in hyperinsulinemia and hypoglycemia.

• An inherited autosomal recessive syndrome characterized by the disorganized formation of new islets in the pancreas and congenital hyperinsulinism. It is due to focal hyperplasia of pancreatic islet cells budding off from the ductal structures and forming new islets of langerhans. Mutations in the islet cells involve the potassium channel gene kcnj11 or the atp-binding cassette transporter gene abcc8, both on chromosome 11.

Details

• E16.9 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.

• The 2023 edition of ICD-10-CM E16.9 became effective on October 1, 2022.

• This is the American ICD-10-CM version of E16.9 – other international versions of ICD-10 E16.9 may differ.