E22.2

Approximate Synonyms

• Syndrome inappropriate antidiuretic hormone secretion

• Syndrome of inappropriate vasopressin secretion

Clinical Information

• A condition of hyponatremia and renal salt loss attributed to overexpansion of body fluids resulting from sustained release of antidiuretic hormones which stimulates renal resorption of water. It is characterized by normal kidney function, high urine osmolality, low serum osmolality, and neurological dysfunction. Etiologies include adh-producing neoplasms, injuries or diseases involving the hypothalamus, the pituitary gland, and the lung. This syndrome can also be drug-induced.

• A syndrome characterized by abnormal secretion of antidiuretic hormone in conjunction with neoplastic growth occurring anywhere in the body.

Details

• E22.2 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.

• The 2023 edition of ICD-10-CM E22.2 became effective on October 1, 2022.

• This is the American ICD-10-CM version of E22.2 – other international versions of ICD-10 E22.2 may differ.