E25.0

Applicable To

• Congenital adrenal hyperplasia

• 21-Hydroxylase deficiency

• Salt-losing congenital adrenal hyperplasia

Approximate Synonyms

• 3 beta-hydroxysteroid dehydrogenase deficiency

• Adrenal hyperplasia, congenital

• Adrenal hyperplasia, congenital, simple virilizing

• Adrenal hyperplasia, congenital, virilizing, non salt

• Congenital adrenal hyperplasia

• Congenital adrenal hyperplasia, undervirilized xy due to 17-alpha hydroxylase deficiency

• Congenital adrenal hyperplasia, virilizing, non-salt-losing

• Congenital adrenal hyperplasia, virilizing, salt-losing

• Late onset congenital adrenal hyperplasia

• Steroid 21-monooxygenase deficiency, simple virilizing type

• Undervirilized xy, 3-beta hydroxysteroid deficiency

• Undervirilized xy, congenital adrenal hyperplasis,

Clinical Information

• A genetic disorder characterized by defects in the synthesis of cortisol and/or aldosterone, resulting in hyperplasia of the adrenal cortical cells.

• A group of inherited disorders of the adrenal glands, caused by enzyme defects in the synthesis of cortisol hydrocortisone) and/or aldosterone leading to accumulation of precursors for androgens. Depending on the hormone imbalance, congenital adrenal hyperplasia can be classified as salt-wasting, hypertensive, virilizing, or feminizing. Defects in steroid 21-hydroxylase; steroid 11-beta-hydroxylase; steroid 17-alpha-hydroxylase; 3-beta-hydroxysteroid dehydrogenase 3-hydroxysteroid dehydrogenases); testosterone 5-alpha-reductase; or steroidogenic acute regulatory protein; among others, underlie these disorders.

• Group of syndromes caused by inherited defects in cortisol and/or aldosterone biosynthesis; acth elevation is caused by low levels of cortisol, whose production is impaired by absence or deficiency of one of the five enzymes necessary for its synthesis from cholesterol.

Details

• E25.0 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.

• Short description: Congenital adrenogenital disorders assoc w enzyme deficiency

• The 2023 edition of ICD-10-CM E25.0 became effective on October 1, 2022.

• This is the American ICD-10-CM version of E25.0 – other international versions of ICD-10 E25.0 may differ.