E26.81

Approximate Synonyms

• Bartter syndrome

• Pseudoprimary hyperaldosteronism

Clinical Information

• A group of disorders caused by defective salt reabsorption in the ascending loop of henle. It is characterized by severe salt-wasting, hypokalemia; hypercalciuria; metabolic alkalosis, and hyper-reninemic hyperaldosteronism without hypertension. There are several subtypes including ones due to mutations in the renal specific sodium-potassium-chloride symporters.

• A rare inherited syndrome characterized by juxtaglomerular cell hyperplasia, hyperaldosteronism, hypokalemia, and alkalosis. Patients have high levels of plasma renin concentration which is not associated with hypertension.

• Hypertrophy and hyperplasia of the juxtaglomerular apparatus with secondary hyperaldosteronism with normal blood pressure and hyperkalemic alkalosis in the absence of edema. Most patients show growth and mental retardation. Nephrocalcinosis and hypercalcinuria occur in some cases. Diuretic abuse may produce a syndrome with similar characteristics pseudo-bartter or factitious bartter syndrome).

• Transmitted as an autosomal recessive trait; characterized by hypertrophy and hyperplasia of the juxtaglomerular cells, and increased concentrations of renin, angiotensin ii, and aldosterone in the absence of edema and hypertension.

Details

• E26.81 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.

• The 2023 edition of ICD-10-CM E26.81 became effective on October 1, 2022.

• This is the American ICD-10-CM version of E26.81 – other international versions of ICD-10 E26.81 may differ.