E53.8

Applicable To

• Biotin deficiency

• Cyanocobalamin deficiency

• Folate deficiency

• Folic acid deficiency

• Pantothenic acid deficiency

• Vitamin B12 deficiency

Approximate Synonyms

• Cerebral degeneration due to vitamin b12 deficiency

• Cobalamin deficiency

• Folic acid deficiency

• Neuropathy due to vitamin b12 deficiency

• Peripheral nerve disorder due to vit b12 deficiency

• Polyneuropathy multiple nerve disorder)

• Polyneuropathy due to vitamin b deficiency

• Subacute combined degeneration of spinal cord

• Subacute degeneration of spinal cord due to vitamin b12 deficiency

• Vitamin b12 deficiency

Clinical Information

• A nutritional condition produced by a deficiency of folic acid in the diet. Many plant and animal tissues contain folic acid, abundant in green leafy vegetables, yeast, liver, and mushrooms but destroyed by long-term cooking. Alcohol interferes with its intermediate metabolism and absorption. Folic acid deficiency may develop in long-term anticonvulsant therapy or with use of oral contraceptives. This deficiency causes anemia, macrocytic anemia, and megaloblastic anemia. It is indistinguishable from vitamin b 12 deficiency in peripheral blood and bone marrow findings, but the neurologic lesions seen in b 12 deficiency do not occur. merck manual, 16th ed)

• A nutritional condition produced by a deficiency of vitamin b 12 in the diet, characterized by megaloblastic anemia. Since vitamin b 12 is not present in plants, humans have obtained their supply from animal products, from multivitamin supplements in the form of pills, and as additives to food preparations. A wide variety of neuropsychiatric abnormalities is also seen in vitamin b 12 deficiency and appears to be due to an undefined defect involving myelin synthesis. from cecil textbook of medicine, 19th ed, p848)

• Condition due to a deficiency of vitamin b12.

• State in which folate is absent or in diminished amount relative to the normal requirement of an organism or a biologic system.

Details

• E53.8 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.

• The 2023 edition of ICD-10-CM E53.8 became effective on October 1, 2022.

• This is the American ICD-10-CM version of E53.8 – other international versions of ICD-10 E53.8 may differ.