H47.22

Applicable To

• Leber’s optic atrophy

Approximate Synonyms

• Bilateral hereditary optic atrophy

• Leber’s optic atrophy

• Lebers optic atrophy

• Left hereditary optic atrophy

• Right hereditary optic atrophy

Clinical Information

• A hereditary disorder caused by mitochondrial mutations, resulting in the degeneration of the retinal ganglion cells and optic atrophy. It is characterized by an acute or subacute loss of central vision. It may initially affect one eye only, but eventually the central loss of vision becomes bilateral.

• A maternally linked genetic disorder that presents in mid-life as acute or subacute central vision loss leading to central scotoma and blindness. The disease has been associated with missense mutations in the mtdna, in genes for complex i, iii, and iv polypeptides, that can act autonomously or in association with each other to cause the disease. from online mendelian inheritance in man, http://www.ncbi.nlm.nih.gov/omim/, mim#535000 april 17, 2001))

• Hereditary conditions that feature progressive visual loss in association with optic atrophy. Relatively common forms include autosomal dominant optic atrophy optic atrophy, autosomal dominant) and leber hereditary optic atrophy optic atrophy, hereditary, leber).

Details

• H47.22 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.

• The 2023 edition of ICD-10-CM H47.22 became effective on October 1, 2022.

• This is the American ICD-10-CM version of H47.22 – other international versions of ICD-10 H47.22 may differ.