A chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin ige), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee. In infants it is known as infantile eczema.
Chronic inflammatory skin disorder in individuals with a hereditary predisposition to a lowered threshold to pruritus; characterized by extreme itching, leading to scratching and rubbing that result in typical lesions of eczema.