M35.1

Applicable To

• Mixed connective tissue disease

Approximate Synonyms

• Mixed collagen vascular disease

• Mixed connective tissue disease

Clinical Information

• A syndrome with overlapping clinical features of systemic lupus erythematosus, scleroderma, polymyositis, and raynaud’s phenomenon. The disease is differentially characterized by high serum titers of antibodies to ribonuclease-sensitive extractable saline soluble) nuclear antigen and a “speckled” epidermal nuclear staining pattern on direct immunofluorescence.

• An autoimmune overlap syndrome characterized by the presence of symptoms of systemic lupus erythematosus, systemic scleroderma, and polymyositis.

Details

• M35.1 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.

• The 2023 edition of ICD-10-CM M35.1 became effective on October 1, 2022.

• This is the American ICD-10-CM version of M35.1 – other international versions of ICD-10 M35.1 may differ.