M88

Osteitis deformans [Paget’s disease of bone]

A chronic condition in which both the breakdown and regrowth of bone are increased. Paget disease of bone occurs most frequently in the pelvic and leg bones, skull, and lower spine. It is most common in older individuals, and may lead to bone pain, deformities, and fractures.

A disease marked by repeated episodes of increased bone resorption followed by excessive attempts at repair, resulting in weakened, deformed bones of increased mass.

A disease marked by repeated episodes of increased bone resorption followed by excessive attempts at repair, resulting in weakened, deformed bones of increased mass. The resultant architecture of the bone assumes a mosaic pattern in which the fibers take on a haphazard pattern instead of the normal parallel symmetry.

A disease of bone that initially results in the excessive resorption of bone by osteoclasts) followed by the replacement of normal bone marrow with vascular and fibrous tissue.

A disease of bone that initially results in the excessive resorption of bone by osteoclasts) followed by the replacement of normal bone marrow with vascular and fibrous tissue. on-line medical dictionary)

Disease marked by repeated episodes of increased bone resorption followed by excessive repair, resulting in weakened, deformed bones of increased mass.

Paget’s disease of bone causes your bones to grow larger and weaker than normal. They also might break easily. The disease can lead to other health problems, too, such as arthritis and hearing loss. You can have paget’s disease in any bone, but it is most common in the spine, pelvis, skull and legs. The disease might affect one or several bones, but not your entire skeleton. More men than women have the disease. It is most common in older people. Many people do not know they have paget’s disease because their symptoms are mild. For others, symptoms can include