N25.1

Approximate Synonyms

• Partial nephrogenic diabetes insipidus

Clinical Information

• A genetic or acquired polyuric disorder characterized by persistent hypotonic urine and hypokalemia. This condition is due to renal tubular insensitivity to vasopressin and failure to reduce urine volume. It may be the result of mutations of genes encoding vasopressin receptors or aquaporin-2 aquaporins); kidney diseases; adverse drug effects; or complications from pregnancy.

• Diabetes insipidus caused by insensitivity of the kidneys to antidiuretic hormone.

• Polyuric disorder characterized by normal rates of renal filtration and solute excretion, but a persistent hypotonic urine due to the failure of renal tubules to respond to antidiuretic hormones, such as vasopressin, to reduce urine volume; tubular insensitivity to vasopressin can result from genetic defects, diseases, drug effects, or may occur with pregnancy.

Details

• N25.1 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.

• The 2023 edition of ICD-10-CM N25.1 became effective on October 1, 2022.

• This is the American ICD-10-CM version of N25.1 – other international versions of ICD-10 N25.1 may differ.