P91.2

ICD-10-CM Coding Rules

• P91.2

Applicable To

• Periventricular leukomalacia

Approximate Synonyms

• Periventricular leukomalacia

Clinical Information

• Degeneration of white matter adjacent to the cerebral ventricles following cerebral hypoxia or brain ischemia in neonates. The condition primarily affects white matter in the perfusion zone between superficial and deep branches of the middle cerebral artery. Clinical manifestations include vision disorders; cerebral palsy; paraplegia; seizures; and cognitive disorders. from Adams et al., Principles of Neurology, 6th ed, p1021; Joynt, Clinical Neurology, 1997, ch4, pp30-1)

• Necrosis and softening of the white matter around the ventricles in the brain. It is usually seen in preterm infants and caused by lack of blood flow and oxygenation in the periventricular brain parenchyma.

Details

• P91.2 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.

• The 2023 edition of ICD-10-CM P91.2 became effective on October 1, 2022.

• This is the American ICD-10-CM version of P91.2 – other international versions of ICD-10 P91.2 may differ.