V09.9

ICD-10-CM Coding Rules

• V09.9

Clinical Information

• Diminished or failed response of an organism, disease or tissue to the intended effectiveness of a chemical or drug. It should be differentiated from drug tolerance which is the progressive diminution of the susceptibility of a human or animal to the effects of a drug, as a result of continued administration.

• Mechanisms, functions, activities, or processes exhibited by tumors or pathogens to withstand previously toxic drugs.

• Obsolete was not defined before being made obsolete). [goc:go_curators]

• Tendency of biological systems organisms, cells, or cell-free systems) to fail to respond as expected to drug treatment or exposure; may be due to specific enzymes, transporters, or receptors which block drug action.

• The failure of cancer cells, viruses, or bacteria to respond to a drug used to kill or weaken them. The cells, viruses, or bacteria may be resistant to the drug at the beginning of treatment, or may become resistant after being exposed to the drug.

Details

• V09.9 should not be used for reimbursement purposes as there are multiple codes below it that contain a greater level of detail.

• The 2023 edition of ICD-10-CM V09.9 became effective on October 1, 2022.

• This is the American ICD-10-CM version of V09.9 – other international versions of ICD-10 V09.9 may differ.