D47.4

Applicable To

• Chronic idiopathic myelofibrosis

• Myelofibrosis idiopathic) with myeloid metaplasia)

• Myelosclerosis megakaryocytic) with myeloid metaplasia

• Secondary myelofibrosis in myeloproliferative disease

Approximate Synonyms

• Myelofibrosis with myeloid metaplasia

• Myelosclerosis with myeloid metaplasia

Clinical Information

• A chronic myeloproliferative neoplasm characterized by bone marrow fibrosis, proliferation of atypical megakaryocytes and granulocytes in the bone marrow, anemia, splenomegaly, and extramedullary hematopoiesis. The cause is unknown. The median survival time is 3-5 years from diagnosis. who, 2001)

• A de novo myeloproliferation arising from an abnormal stem cell. It is characterized by the replacement of bone marrow by fibrous tissue, a process that is mediated by cytokines arising from the abnormal clone.

• A progressive, chronic disease in which the bone marrow is replaced by fibrous tissue and blood is made in organs such as the liver and the spleen, instead of in the bone marrow. This disease is marked by an enlarged spleen and progressive anemia.

Details

• D47.4 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.

• The 2023 edition of ICD-10-CM D47.4 became effective on October 1, 2022.

• This is the American ICD-10-CM version of D47.4 – other international versions of ICD-10 D47.4 may differ.